Old interview [ 01/21/2003 ], but it is interesting to see Wolfram [
http://en.wikipedia.org/wiki/Stephen_Wolfram ], creator of Mathematica, thinking about how to model the execution of the code called genome... we have reached the second half of 2007... Mr. Wolfram, any news?
Wolfram: Bioinformatics has traditionally concentrated on handling genomic data---mostly in the form of strings. What's now starting in computational biology is the study of actual processes that operate in biological systems. The things I've discovered in writing A New Kind of Science suggest a framework for thinking about such processes. The key idea is to think in terms of simple programs---and to use those to capture the essential mechanisms in biological systems. From genomics we know the lowest level code for biological organisms; now we have to have models for how that code actually runs.
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