Session opened with
Erick Denamur talking about insertion and deletion hotspots of E.coli. He also talked about the
coliscope consortium which is "a sequencing project for the understanding of commensalism and virulence emergence in the Escherichia coli/Shigella species". Then the mic was handed to
Carmen Buchrieser who highlighted the importance of Legionella which made the
Queen run back to the palace. The following talk was from
Tim Stinear who mentioned how poking finger(s) into fish can lead to Mycobacterium marinum (which along with M.ulcerans, is closest to M.tuberculosis giving positive mantoux test) infection! He also mentioned about
Gene Spaghetti a cool tool for "visualizing base and amino acid usage in a genome", COG's 3-way genome blast approach and synteny map generation.
Image via WikipediaThen came
Marrion karrasch who talked about ERA-NET PathoGenoMics, Interferon interference (?), invasive propeties of C.albican (with liver capsule invasion as an example) and RNAi for possible therapeutic approach (?). Again thanks to
Swati for the better notes below:
Population phylogenomics of the E.coli species
Erick Denamur, medical faculty Xavier Bichat, Paris
- Phylogeny of complete genome within species.
- Majority of E.coli strain can be assigned to one of 4 main phylogenetic groups (A, B1, B2 and D).
- These 4 phylogenetic groups differ in their phenotypic and genotypic characteristics.
- Gene conversion doesn’t affect the tree topology.
- E.coli ancestor is close to K-12
Comparative Genomics of Legionella pneumophila and Legionells longbeachae, ttwo human pathogens that coevolved with protozoa.
Carmen Buchrieser, Pasteur Institute, Paris
- Analysed and compared the whole genome to understand the pathogencity. Session 8: Comparative Genomics and Evolution | | Erick Denamur, Medical Faculty Xavier Bichat, Paris, France
Population phylogenomics of the Escherichia coli species | Carmen Buchrieser, Institut Pasteur, Paris, France
Comparative genomics of Legionella pneumophila and Legionella longbeachae, two human pathogens that coevolved with protozoa | Tim Stinear, Monash University, Victoria, Australia
Insight into tuberculosis and Buruli ulcer from the complete genome sequence of Mycobacterium marinum | | Pathogenomics PhD award |
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Image via WikipediaThen came Marrion karrasch who talked about ERA-NET PathoGenoMics, Interferon interference (?), invasive propeties of C.albican (with liver capsule invasion as an example) and RNAi for possible therapeutic approach (?). Again thanks to Swati for the better notes below:
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