Thursday, April 17, 2008

Conference: Genomes 2008 (11 th April) - Closing Session


The last session started with Hilde De Reuse talking about "Nickel trafficking in the gastric pathogen Helicobacter pylori". She talked about gastric colonization of H.pylori and its secret survival weapon, the Urease. She also mentioned that she will never like her child to be infected with this nasty bug called H.pylori ( c.f. Martin J. Blaser opening talk).
Uri Gophna [ about "Complexity, connectivity, and the fate of laterally acquired genes". His analysis on horizontal gene transfer using E.coli as model challenged the Complexity theory (genes coding for protein which form part of protein complex in donor genome do not tend to successfully integrate in recipient genome) and came up with Balance theory (protein coded by transferred genes integrate gradually into pre-existing protein complexes in recipient). Mark Pallen [ about "Escherchia coli: Pathogenomics of a model organism" and argued that O-island 115 is a deletion in K12 and not a insertion in O157:H7 E.coli strain. Ben Adler [ about "What can we learn from comparative genomics of Leptospira species?". He started his talk by pointing to the fact that what Leptospira might be thinking about sequencing..."you have got my gene, but you don't really know me"!
This fine conference ended with the closing talk from Frank Kunst :)

Its time to walk in the streets of Paris now ...
Session 8: Comparative Genomics and Evolution
Chair: Xavier Nassif, Necker Hospital, Paris, France

Hilde De Reuse, Institut Pasteur, Paris, France
Nickel trafficking in the gastric pathogen Helicobacter pylori

Uri Gophna, University of Tel Aviv, Tel Aviv, Israel
Complexity, connectivity, and the fate of laterally acquired genes
Mark Pallen, The University of Birmingham, Birmingham, United Kingdom
Escherchia coli: Pathogenomics of a model organism
Ben Adler, Monash University, Victoria, Australia
What can we learn from comparative genomics of
Leptospira species?
Closing lecture
Frank Kunst, Institut Pasteur, France

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